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Innovate

Discover the latest innovations in computer-aided reasoning and information systems.

A new life in Leeds at Lhasa 4

Key insights from the Lhasa Limited & IPEC Europe Nitrites meeting

Explore key insights from the Lhasa Limited and IPEC Europe Nitrites meeting, where attendees discussed advancing nitrosamine understanding.   “The meeting provided an opportunity to share our common difficulties and discuss solutions to establish robust and accurate methods for analysing nitrites in excipients.” We recently welcomed members of the Lhasa Nitrites data sharing consortium and […]

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Supporting the safe use of CDB in skincare products using Derek Nexus

Supporting the safe use of CBD in skincare products using Derek Nexus

Cannabidiol (CBD) is gaining prominence as a sought-after ingredient in skincare and beauty formulations, thanks to its notable anti-inflammatory, antioxidant and anti-bacterial properties. Derived directly from the hemp plant, this compound is increasingly being used as an ingredient in skincare products, particularly for the management of various skin conditions like eczema, dermatitis and psoriasis. Despite

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Have you read this? Benchmarking In silico prediction of pharmaceutical degradation pathways

We are delighted to share our important new open access article: In silico prediction of pharmaceutical degradation pathways: A benchmarking study using the software program Zeneth. The paper, recently published in Organic Process Research & Development (OPRD) is authored by Lhasa Principal Scientist Rachel Hemingway, alongside industry expert co-authors from AstraZeneca, GSK, Pfizer, BMS, Amgen

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zeneth blog

Safeguarding Pharmaceutical Development: The Importance of Early Risk Mitigation

Ensuring the safety and efficacy of active pharmaceutical ingredients (APIs) is of paramount importance. A critical aspect of this process involves the identification and mitigation of potentially mutagenic impurities, like nitrosamines. In this blog, we will explore the significance of risk mitigation at the early stages of API development and introduce a cutting-edge solution, Zeneth,

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Mitigating the risks of NDSRI’s through data sharing

At Lhasa, we believe in the transformative power of knowledge sharing as the driving force to support the global challenge of nitrosamine risk assessment. Through data sharing and industry collaboration, we empower members to further understand the risks associated with their potential nitrosamine impurities. The Vitic Complex Nitrosamines initiative, launched in 2021 in response to

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NIHS collaboration: revolutionising chemical safety assessment and reducing animal testing reliance.

NIHS collaboration: revolutionising chemical safety assessment and reducing animal testing reliance

Have you read our collaborative paper, published with the National Institute of Health Sciences (NIHS) of Japan? The paper is based on our shared project to improve in silico developmental and reproductive toxicity (DART) predictions, to safely move towards replacing traditional animal testing for chemical safety assessments. “The outcome of this collaborative and innovation project

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