Regulatory frameworks like ICH M7 have established in silico tools as a trusted method for evaluating the mutagenic potential of impurities, reducing reliance on animal testing and accelerating risk assessments. While these tools are widely accepted for mutagenicity, researchers and regulators are now looking at their potential for broader genotoxicity evaluations, including chromosome damage.
As the use of in silico methods continues to evolve, there is growing interest in how they can support pesticide metabolite and impurity assessments. There is an increasing push to incorporate in silico genotoxicity evaluations into regulatory decision-making.
Join us for this insightful webinar, where our expert speakers will explore how computational tools can support chromosome damage assessment. You’ll hear from a regulator, agrochemical industry professional and scientist on how in silico models are shaping the future of genotoxicity risk assessment.
Register below to gain valuable insights into the evolving role of in silico tools in genotoxicity assessment!
Webinar agenda
- The role of in silico tools in pesticide & residue assessments
- Glenn Lurman from BfR will discuss the importance of in silico tools in pesticide risk assessments, including their role in evaluating chromosome damage and mutagenicity.
2. Using Derek Nexus & Sarah Nexus for assessments of genotoxicity
- Robert Foster from Lhasa Limited will introduce expert-based and statistical toxicity prediciton tools Derek Nexus and Sarah Nexus. Rob will showcase how they predict for mutagenicity and in vitro chromosome damage, including all chromosomal aberrations, supporting in silico adoption for pesticide metabolites and impurities assessment.
3. Industry case study: Applying Sarah Nexus in agrochemicals
- Katy Bridgwood from Syngenta will present a real-world case study on using Sarah Nexus within an agrochemical workflow for genotoxicity assessment.
4. Q&A session
- Open discussion where you can ask questions and engage with our expert speakers.