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Publications

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Date

Infographic

Accelerating safety assessments for carcinogenicity with Kaptis

  • Oct 2024
  • Carcinogenicity assessment

Paper

Industrial Genotoxicology Group (IGG): 36th Annual Meeting Report

  • Oct 2024
  • Nitrosamine impurity risk assessment

Paper

Reactivities of N-Nitrosamines against Common Reagents and Reaction Conditions

  • Sep 2024
  • Nitrosamine impurity risk assessment

QMRF

Derek Nexus 6.4 Carcinogenicity QMRF

  • Sep 2024
  • Carcinogenicity assessment

QMRF

Derek Nexus version 6.4 Teratogenicity QMRF

  • Sep 2024

QMRF

Derek Nexus version 6.4 HERG QMRF

  • Sep 2024

QMRF

Sarah Nexus 4.0 Chromosome Damage QMRF

  • Sep 2024
  • Genotoxic impurity evaluation

QMRF

Sarah Nexus version 4.0 Mutagenicity QMRF

  • Sep 2024
  • In silico mutagenicity assessment

QMRF

Derek Nexus version 6.4 Chromosome damage QMRF

  • Sep 2024
  • Genotoxic impurity evaluation

QMRF

Derek Nexus version 6.4 Skin sensitisation QMRF

  • Sep 2024
  • Skin sensitisation assessment

Paper

A developmental and reproductive toxicity adverse outcome pathway network to support safety assessments

  • Aug 2024
  • Safety profiling in drug discovery

Paper

Leveraging ICH M7 Control Options 3 and 4: Discussion and Clarification Using Industrial Case Studies

  • Jul 2024
  • Impurity and degradant control, Nitrosamine impurity risk assessment

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  • Solution

  • Publication Type

  • Date

Infographic

Anticipating and mitigating adverse drug reactions through machine learning and privacy-preserving data sharing (infographic)

  • Nov 2020
  • Data sharing, Safety profiling in drug discovery

Infographic

Could purge calculations support your regulatory submissions? (Infographic)

  • Oct 2020
  • Impurity and degradant control

Paper

The importance of expert review to clarify ambiguous situations for (Q)SAR predictions under ICH M7

  • Sep 2020
  • In silico mutagenicity assessment

Paper

Introducing the concept of virtual control groups into preclinical toxicology testing 

  • Sep 2020
  • Data sharing, eTox

Presentation

ICH M7 Expert Review Workshop: Resolving common prediction scenarios using automated arguments in Nexus 2.3 (Webinar Presentation Slides) 

  • Sep 2020
  • In silico mutagenicity assessment

Paper

Are all nitrosamines concerning? A review of mutagenicity and carcinogenicity data 

  • Aug 2020
  • Carcinogenicity assessment, In silico mutagenicity assessment, Nitrosamine impurity risk assessment

Infographic

Who is using Vitic? Infographic

  • May 2020
  • Non-genotoxic impurity assessment

Infographic

Vitic Data Sharing Benefits

  • May 2020
  • Data sharing, Non-genotoxic impurity assessment

Infographic

Mirabilis Cost Saving Infographic

  • Apr 2020
  • Impurity and degradant control

Poster

From Private Data to Shared Knowledge

  • Mar 2020
  • Safety profiling in drug discovery

Poster

Consortium-led federated QSAR models for secondary pharmacology – preparing the data

  • Mar 2020
  • Safety profiling in drug discovery

Poster

Utilising Adverse Outcome Pathways as a Framework to Organise Evidence and Support Carcinogenicity Risk Assessment

  • Mar 2020
  • Carcinogenicity assessment
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